Mistral Nemo 12B quants compared

22 real GGUF builds of Mistral Nemo 12B measured from bartowski/Mistral-Nemo-Instruct-2407-GGUF. Download the Q4_K_M (6.96 GB) unless you know why you need heavier. Probed 2026-09-02.

Download Mistral Nemo 12B Q4_K_M (6.96 GB). It fits 12 GB of memory with 16k context. With Ollama: ollama run mistral-nemo:12b

Every Mistral Nemo 12B quant by real file size

QuantWeights+ KV (16k)TotalFits comfortably inQuality
F3245.63 GB3.0 GB48.6 GB64 GBFull precision (lossless)
F1622.82 GB3.0 GB25.8 GB32 GBFull precision (lossless)
Q8_012.13 GB3.0 GB15.1 GB24 GBNear-lossless
Q6_K_L9.67 GB3.0 GB12.7 GB16 GBExcellent
Q6_K9.37 GB3.0 GB12.4 GB16 GBExcellent
Q5_K_L8.51 GB3.0 GB11.5 GB16 GBVery high
Q5_K_M8.13 GB3.0 GB11.1 GB16 GBVery high
Q5_K_S7.93 GB3.0 GB10.9 GB16 GBVery high
Q4_K_M *6.96 GB3.0 GB10.0 GB12 GBHigh: the default pick
Q4_K_L7.43 GB3.0 GB10.4 GB12 GBHigh
Q4_K_S6.63 GB3.0 GB9.6 GB12 GBHigh
Q4_06.61 GB3.0 GB9.6 GB12 GBHigh
IQ4_XS6.28 GB3.0 GB9.3 GB12 GBHigh
Q3_K_XL6.66 GB3.0 GB9.7 GB12 GBAcceptable: visible loss
Q3_K_L6.11 GB3.0 GB9.1 GB12 GBAcceptable: visible loss
Q3_K_M5.67 GB3.0 GB8.7 GB12 GBAcceptable: visible loss
IQ3_M5.33 GB3.0 GB8.3 GB12 GBAcceptable: visible loss
Q3_K_S5.15 GB3.0 GB8.2 GB12 GBAcceptable: visible loss
IQ3_XS4.94 GB3.0 GB7.9 GB12 GBAcceptable: visible loss
Q2_K_L5.07 GB3.0 GB8.1 GB12 GBExperimental: not ranked: never recommended
Q2_K4.46 GB3.0 GB7.5 GB12 GBExperimental: not ranked: never recommended
IQ2_M4.13 GB3.0 GB7.1 GB8 GBExperimental: not ranked: never recommended

* default pick. Weights = real GGUF file sizes from bartowski/Mistral-Nemo-Instruct-2407-GGUF (probed 2026-09-02). KV = fp16 estimate; a q8_0 cache roughly halves it. "Comfortable" = weights + KV within 90% of memory.

Best Mistral Nemo 12B quant by memory

MemoryRecommended quantTotal (16k ctx)
12 GBQ4_K_M10.0 GB
16 GBQ6_K12.4 GB
24 GBQ8_015.1 GB
32 GBF1625.8 GB

Why we don't rank Mistral Nemo 12B's 2-bit quants

Quants at 2 bits per weight or below (Q2_K, IQ2, IQ1, TQ1) cut file size by roughly half versus Q4, but the quality collapse is steep and non-linear: perplexity spikes, instruction-following degrades, and hallucinations rise. A model that answers faster but wrong is not a smaller model: it is a worse one. ModelFit lists these builds for completeness but never ranks or recommends them.

Run Mistral Nemo 12B on your GPU

Frequently asked questions

What is the best quantization of Mistral Nemo 12B?

Q4_K_M is the default pick: 6.96 GB of weights, high: the default pick quality, fitting comfortably in 12 GB of memory (weights + 16k context KV-cache). Go Q6_K or Q8_0 if you have headroom.

How much memory does Mistral Nemo 12B need?

At Q4_K_M, Mistral Nemo 12B needs 6.96 GB for the weights plus ~3.0 GB of KV-cache at 16k context, about 10.0 GB total, so a 12 GB card or Mac (90% usable budget) runs it comfortably.

Should I use a Q2_K or IQ2 quant of Mistral Nemo 12B?

No. Mistral Nemo 12B at 2 bits per weight is a visibly worse model. Quality collapse at that bitrate is steep, not gradual. If only a 2-bit build fits your memory, run a smaller model at Q4_K_M instead. ModelFit lists these builds but never recommends them.

Cite this page

ModelFit: Mistral Nemo 12B quantization comparison (real GGUF file sizes).
https://modelfit.io/quant-compare/mistral-nemo-12b/ (data probed 2026-09-02, CC BY 4.0).